Furthermore, inactivation of key androgenic enzymes, such as 3-hydroxysteroid dehydrogenase and 17-hydroxysteroid dehydrogenase, together with decreased testosterone synthesis suggest a potential impairment of male gonadal function
Following Fourier transformation with 0.3 Hz line broadening and a zero-filling to 64 K, ACD Lab Processor Academic Edition (Advanced Chemistry Development, 12.01, 2010) was used to perform phase adjustment and baseline correction of 1 H-NMR spectra as well as to set spectral chemical shift referencing on the TSP CH 3 signal at 0.00 ppm
The binding of -syn to GAPDH with partially oxidized active site cysteines leads to the inactivation of the enzyme
Matching was based on a propensity-score model that utilized 42 observable baseline covariates, and matched controls were selected based on a caliper width of 0.1
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